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A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2

Journal Article

A lingering question in developmental biology has centered on how transcription factors with widespread distribution in vertebrate embryos can perform tissue-specific functions. Here, using the murine hindlimb as a model, we investigate the elusive...

Amanda Papakyrikos

Person

I am interested in the genetic and molecular mechanisms that underlie human development. Currently, I am working on two projects for my senior thesis, involving circadian rhythms and incremental growth line formation in teeth. In collaboration with Dr...

Parallel Evolution at the Regulatory Base-Pair Level Contributes to Mammalian Interspecific Differences in Polygenic Traits.

Journal Article

Parallel evolution occurs when distinct lineages with similar ancestral states converge on a new phenotype. Parallel evolution has been well documented at the organ, gene pathway, and amino acid sequence level but in theory, it can also occur at...

Julia Boughner, Ph.D.

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Doug Menke, Ph.D.

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Phil Reno, Ph.D.

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Nathan Young, Ph.D.

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Andrew Doxey, Ph.D.

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Craig Lowe, Ph.D.

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Neil Roach, Ph.D.

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Michael Hiller, Ph.D.

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